Pathophysiology MCQs/BCQs

1) Total body water is:
1. 14L
2. 42L
3. 20 L
4. 28 L

2) All of the following are benign tumors, the most unlikely is:
1. Adenocarcinoma
2. Meningioma
3. Fibroma
4. Leiomyoma

3) Neutrophils predominate in acute inflammatory infiltrate during:
1. First 06 -24 hours
2. First 08 hours
3. First 04- 06 hours
4. First 24-48 hours

4) Most effective Bactericidal system in neutrophils is:
1. Halideion
2. MPOsystem (Myeloperoxidase)
3. NADPHoxidasesystem
4. MP0-H202Halidesystem

5) What is the most important prognostic factor for human cancer is proved to be of greater clinical value:
1. Stage
2. Vascular invasion.
3. Lymphocytic infiltration
4. Grade.

6) Most reliable feature that differentiates malignant tumor from benign is:
1. Local invasion
2. Metastasis
3. Irregular surface
4. Capsule

7) Regarding type – I hypersensitity:
1. Initial response is characterized by vasoconstriction
2. Late phase reaction occurs after few minutes
3. Develop after few days
4. Characterized by release of mast cell mediators

8) Reaction due to injection of horse serum (serum sickness) is example of:
1. Type – IV hypersensitivity
2. Type – Il hypersensitivity
3. Type – Ill hypersensitivity
4 Type – I hypersensitivity

9) Antibody mediated hypersensitivity does not occur in:
1. Erythroblastosis fetalis
2. Autoimmune Hemolytic anemia
3. Arthus reaction
4. Transfusion reaction

10) A 50 years old male develops sudden severe abdominal pain radiating to back. His lab values shows raised Amylase level. Regarding this case fat necrosis may occur in which of the following organ:
1. Brain
2. Skeletal muscle
3. Pancrease
4. Heart

 

11) Regarding Necrosis, which of the following statement is true:
1. Pancreas shows coagulative necrosis
2. Heart shows coagulative necrosis
3. Brain shows coagulation Necrosis
4. Heart shows liquefactive necrosis

12) In full term pregnancy, which one of the following cell adaptation has maximum contribution to increase in the size of uterus?
1. Dystrophy
2. Hyperplasia
3. Anaplasia
4. Atrophy

13) AIDS can be transferred through following factors except:

1.Inhalation
2. Blood
3. Direct contact
4. Saliva
14) All of the following are malignant tumors, the most unlikely is
1. Adenocarcinoma
2. Fibrosarcoma
3. Teratoma
4. Leukemia

16) Which of the following complement proteins may act as Opsonins:
1. c3b
2. C3a
3 C5b 9 complex
4. C3a & C5a

17) All of the following are malignant tumors, the most unlikely is:
1. Leukemia
2. Adenocarcinoma
3. Fibrosarcoma
4. Osteoma

18) Which one of the following mediator causes, chemotaxis of the leukocytes?
1. C1
2. C5a
3. c2a
4. C4

19) Granuloma with caseous necrosis is seen in:
1. Lymphoma
2. Tuberculosis
3. Sarcoidosis
4. Foreign body granuloma

20) Which of the following lab diagnostic technique is most convenient and suitable for the initial diagnosis and management of the patient suffering from swelling infront of neck (goiter)?
1 Smear
2. FNAC
3. Immunohistochemistry
4. Biopsy

 

21) ———— is also called Cytotoxic Hypersensitivity because it utilizes antibodies that can destroy normal cells by complement lysis or by antibody-dependent cellular cytotoxicity
1. Type-ll hypersensitivity
2. Type-l hypersensivitiy
3. Type-IV hypersensivitiy
4. Type-ll hypersensivitiy

22) Most common chornic inflammatory cells are:
1. Neutrophils
2. Macrophages
3. Eosinophils
4. Plasma cells

23) Malignant tumor arising from mesenchymal tissue is most likely called as:
1. Adenomna
2. Sarcoma
3. Hepatoma
4. Fibroma

24) Metastasis of cancer most unlikely occur by:
1. Lymphatic spread
2. Direct seeding of body cavities
3. Aerosol droplet
4. Hematogenous spread

25) Regarding anaplasia which of the following statement is true:
1. Nuclear to cytoplasmic ratio 1:6
2. Increase mitosis
3. Well differentiated cells
4. Normal size of shape of cells

26) Laboratory test most commonly used for diagnosis of AIDS is:
1. ELISA
2. EASTERN BLOT
3. RIBA
4. WESTERN BLOT

27) Multiple sclerosis is example of:
1. Type – l hypersensitivity
2. Type- IV hypersensitivity
3. Type-Ill hypersensitivity
4. Type – I hypersensitivity

28) Generalized edema through the body is termed as:
1. Anasarca
2. Anaplasia
3. Sarcoma
4. Pitting edema

29) Major component of innate immunity are all of following, the most unlikely is:
1. Epithelial barrier
2. B-lymphocyte
3. Complement proteins
4. NK cells

30) A 40 years old male suffering from cervical lymphadenopathy. Biopsy report shows granuloma with caseous necrosis. The most likely diagnosis will be
1. Tuberculosis
2. Sarcoidosis
3. Lymphoma
4 Foreign body granuloma

 

31) Pathological hyperplasia of thyroid gland occurs in:
1. Thyroid connective tissue
2. Thyroid follicles
3. Whole thyroid tissue
4. Thyroid stroma

32) A 55 years old female with ovarian Carcinoma developed ascities. Cytological analysiss of ascitic fluid show malignant cells. Which of the following pathway best explaining the spreading of tumor to the peritonium:
1. Seeding of body cavity
2. Lymphatic spread
3. Hematogenous spread
4. Direct Extension

33) Weakness and wasting of the body due to severe chronic illness is referred to:
1. Neoplasm
2. Cachexia
3. Anorexia
4. Fatigue

34) Which of the following is earliest stage of vascular events of acute inflammation?
1. Vasodilation
2. Initial vasoconstriction
3. Redness
4. Leukocytic migration

35) Increased concentration of potassium in the blood is termed as:
1. Hypernatremia
2. Hyperkalemia
3. Hypokalemia
4. Hyponatremia

36) Loss of uniformity of cells & Ioss of arachitectural orientation is most likely called as:
1. Desmoplasia
2. Metaplasia
3. Dysplasia
4. Anaplasia

37) Arthus reaction is example of:
1. Type – lll hypersensitivity
2. Type – II hypersensitivity
3. Type- IV hypersensitivity
4. Type – I hypersensitivity

38) All are causes of atrophy, the most unlikely is:
1. Diminished blood supply
2. Denervation
3. Decrease workload
4. Increase workload

39) Excessive intake of acid containing foods and beverages may lead to development of:
1. Metabolic acidosis
2. Respiratory alkalosis
3. Metbolic alkalosis
4. Respiratory acidosis

40) In full term pregnancy, which one of the following cell adaptations has maximum contribution to increase in the size of uterus?
1. Dystrophy
2. Hyperplasia
3. Anaplasia
4 Atrophy

41) Goodpasture syndrome is example of:
1. Type -Ill hypersensitivityy
2. Type – I hypersensitivity
3. Type-ll hypersensitivity
4. Type – IV hypersensitivity